Starting Monday, Viagra will be facing stiffer competition. Viagra is the brand name for Pfizer's sildanefil, the erectile dysfunction (ED) drug that hit the market in 1998 and made it big, as in over 1.5 billion in revenues in 2016. But Viagra's patent (sildenafil at doses for ED) is scheduled to 비아그라 구입
expire in April 2020, which undoubtedly will give rise to a number of generic versions. But, as CBS News reported previously, a deal negotiated four years ago will allow Teva Pharmaceuticals USA Inc. to begin selling a generic version in the United States on December 11, 2017. Pfizer will counter with their own generic little white pill at half the current $65-a-little-blue-pill price. This milestone could make sildanefil's impact even bigger. Viagra has already changed society in many ways. Prior to Viagra's arrival, hearing ED on television usually meant a시알리스 구입 talking horse or the emergency department. But things changed when the introduction of Viagra came in the year after the Food and Drug Administration (FDA) began allowing direct-to-consumer (DTC) advertising in 1997. Quickly ED went from something which was rarely mentioned (even between patients and doctors) to something that it is hard to miss when you watch any television, especially for more than 4 hours. On the one hand, greater awareness and the availability of a medication option has helped the approximately 18 million men in the United States over the age of 20 who suffer from ED, based on a study published in the American Journal of Medicine led by Elizabeth Selvin, PhD, MPH from https://viagra-onlineshop.com/ the Johns Hopkins Bloomberg School of Public Health. It also may have made it easier for people to discuss sexual health issues in general. Since sexual health is tied with mental, emotional, and physical health, Viagra could make a major difference for someone who has no other remaining options to address their ED. Here's an Associated Press segment on how generic versions of sildanefil will make it more affordable for patients: Today In: BusinessHowever, the introduction of Viagra and its associated marketing has had its side effects. And by side effects, I don't mean aches or pains in the muscles, bloody nose, diarrhea, difficult or labored breathing, flushing, headache, trouble sleeping, sneezing, etc. One issue is what's been dubbed "medical student syndrome". During medical school, many first year students go through a phase in which they are convinced that they have the diseases that they are studying. Hearing about a medical problem frequently enough can make you believe that you have the problem or even actually lead to the problem if the power of suggestion and the mind-body connection happens to be strong enough for that disease. And the mind is definitely connected with that part of the body. So the question is how many men who didn't really have ED ended up being convinced that they actually had it after watching the commercials? PROMOTEDJapan BRANDVOICEKick-starting Japan’s Healthcare Revolution Cloudflare BRANDVOICEExcelling At User Experience: Balancing Cybersecurity With Performance Oracle BRANDVOICEGo Big, Really Big, As High-Performance Cloud Computing Scales To Millions Of JobsA second potential side effect is displacing other possible treatments 비아그라 구매 for ED, especially those focused on lifestyle changes. Eating a healthy diet, getting enough physical activity, decreasing stress, practicing relaxation techniques, improving your sleep, and losing weight can often help with ED. Of course, popping a pill can seem easier and quicker than these other approaches but may not be the best longer-term solution and should not be the first option. Taking medications can help overlook or even mask serious conditions causing the ED such as obesity, diabetes, or cardiovascular disease. Ultimately, treating the underlying cause of ED is usually safer and can be more effective. This Monday, Dec. 4, 2017 photo shows a tablet of Pfizer's Viagra, left, and the company's generic version, sildenafil citrate, at Pfizer Inc., headquarters in New York. The drugmaker is launching its own cheaper generic version of Viagra rather than lose sales when its impotence pill gets its first generic competition. (AP Photo/Richard Drew) A third side effect has been what was originally an ED drug has now become for many a PED, as in a performance enhancing drug, which, in turn, could be artificially raising expectations. Now a number of men who do not suffer from ED use Viagra (or Cialis or Levitra) as a sex aid, sort of like "juicing" for sex. It's a bit like major league baseball when it moved into the 1990's PED/steroids era. The definition of success and entertainment changed. Suddenly 20 to 40 home runs a season was not enough. Getting 60 or even 70 home runs became more of the norm. While they don't keep the same type of statistics for sex as they do for major league baseball (otherwise you may not want to see your batting average or on-base percentage), one has to wonder how using such sex PEDs may have altered the perceptions, dynamics, psychology, emotional aspects, and health of sex. Humans are by nature imperfect. You aren't going to hit a home run every time you get up to bat. Sometimes, you swing and miss or hit a foul ball or bunt. You may even trip while running the bases. A healthy relationship will accommodate and even embrace such imperfections and foibles. However, anything that can result in an erection lasting for 3 hours and 59 minutes and technically still be OK, could really change how people interact with each other and feel about themselves. Then, there's how Viagra altered the pharmaceutical industry, becoming basically its first blockbuster "lifestyle" medication. Some have wondered how much Viagra's success has shifted effort and resources away from the development of other medications such as those for infectious diseases and cancer.비아그라 구입 With Viagra about to reach its 20th birthday, there's no question that this little blue pill has already had a big impact. Soon sildanefil will become significantly cheaper and more available. In fact, as Billy Perrigo reported for Time, it will be sold over-the-counter in the United Kingdom. What can only imagine what the next 20 years may bring. 출처 : https://www.forbes.com/sites/brucelee/2017/12/06/viagra-get-ready-for-it-to-becomes-generic-cheaper-and-more-available/#5fbbb3253200
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Don’t. Vape. Your. Viagra.
We had to say it, but we weren’t the first. The US Food and Drug Administration 비아그라 구입 (FDA) issued a written warning to HelloCig Electronic Technology Co. Ltd after the agency had reason to believe the Japan-based vaping company was illegally selling e-liquid products intended for vaping that contained unapproved drugs for erectile dysfunction, as well as weight loss drugs – the company falsely claims both were approved by the FDA. Oops. The FDA says information on the HelloCig website is “directed to consumers and conveys, misleads, or would mislead consumers into believing” the products are approved by the federal agency and, as such, are misbranded under federal law.시알리스 구입 The company’s “E-Cialis HelloCig E-Liquid” was found to contain the prescription drugs tadalafil and sildenafil while the “E-Rimonabant HelloCig E-Liquid” tested positive for sildenafil. Both drugs are approved by the FDA to treat erectile dysfunction under a prescription, not over the counter or in e-liquid products. The two prescriptions are inhibitors that can interact with the nitrates found in prescription drugs used to treat high blood pressure and heart disease in a dangerous way. 煙茄子@nasubin99Hello CigのメカニカルMOD♬ Wotofo Recurve RDA ゴールドがこれにめちゃんこ似合ってるぞ! (≧O≦)ブハァ〜#hellocig #Wotofo #WotofoRecurveRDA #WOTOFOMAN #mikevapes 45 5:42 PM - Oct 8, 2018 Twitter Ads info and privacy See 煙茄子's other Tweets“There are no e-liquids that contain prescription drugs that have been proven safe or effective through this route of administration,” said FDA Commissioner Scott Gottlieb in a statement. 광고Another e-liquid formula made by HelloCig is marketed for weight loss and branded in a way that suggests it contains Acomplia, an anti-obesity drug not approved by the FDA for sale in the US. “Prescription drugs are carefully evaluated and labeled to reflect the risks of the medications and their potential interactions with other medicines, and vaping active drug ingredients is an ineffective route of delivery and can be dangerous,” said Gottlieb. “There are no e-liquid products approved to contain prescription drugs or any other medications that require a doctor’s supervision.”시알리스 구매 It comes after more than 40 e-cigarette products have recently been criticized as the FDA is investigating whether companies are illegally marketing their products to children. Additionally, the agency sent letters to 21 other vape companies, including Vuse Alto, myblu, Myle, Rubi, and STIG. The FDA says HelloCig is in violation of the Federal Food, Drug, and Cosmetic Act. The company has 15 working days to respond with plans to address these concerns. If found guilty, the federal government could issue fines or potentially seize products. . https://viagra-onlineshop.com/ [H/T: Ars Technica] 출처 : https://www.iflscience.com/health-and-medicine/apparently-we-have-to-say-it-please-dont-vape-your-viagra/ President Trump admitted he didn't know about U.S. military spending on Viagra as he defended his ban on transgender military personnel during an interview broadcast on "Good Morning Britain" Monday.비아그라 구입
Details: Show co-host Piers Morgan asked him why he felt the ban was needed, given Trump's recent tweets supporting the LGBTQ community. "Because they take massive amounts of drugs, in the U.S. military you are not allowed to take any drugs," Trump said. "You would have to break rules and regulations in order to have that." Good Morning Britain✔@GMB'You have to have a standard and you have to stick by that standard.' 시알리스 구입 The POTUS defends his decision to ban transgender people from serving in the military.@piersmorgan | #GMBTrump 862 3:38 PM - Jun 5, 2019 Twitter Ads info and privacy 544 people are talking about thisWhat they're saying: Morgan pointed out the U.S. military "spends a lot more money, for example, on giving viagra to servicemen and women, well servicemen, than it does on medical bills for transgender people." The president responded, "I didn’t know they did that." Context: The Military Times reported in 2017 the Defense Department spent $84.2 million on erectile dysfunction medications such as Viagra — 10 times more than it spent on health care services for transgender personnel. https://viagra-onlineshop.com/
The "little blue pill" celebrates its 20-year anniversary. It started out as a drug for erectile dysfunction, but it’s now taken by younger men for performance anxiety.
Share on Pinterest Photo: Christopher Furlong | Getty ImagesAfter 20 years, is Viagra now a young man’s drug? Pfizer’s famous blue pill was approved on March 27, 1998 as the first oral treatment available for erectile dysfunction in the United States.비아그라 구입 Billions and billions of dollars in sales later, the drug is now even more ubiquitous. And its users appear to be getting younger. But, for this next generation of men, the drug is being taken for reasons beyond the initial scope of erectile dysfunction. Some studies have suggested that younger men who take Viagra take it to deal with psychological barriersTrusted Source, including stress and anxiety surrounding sex such as “performance anxiety.” 광고Others take it recreationally to aid in sexual encounters among men as essentially a party drug that can increase sexual performance. In these circumstances, it is often taken alongside other drugs as well. But the question is, should young men be taking a drug to deal with their nerves or to perform better during sex? And furthermore, is it even safe? Viagra reflects changes in sexual cultureHealthline spoke with two sexual health experts and got differing opinions on whether or not it’s a good idea. However, both experts agreed that the surging interest in Viagra has a lot to say about how sexual culture in the United States has developed over the past two decades. “Sexual rights of women have been more of a focus in the media and in the whole sociocultural context right now. When a man enters a relationship or a dating scenario these days, sex is not something that you shy away from, and it might be good or not. Sex is actually a component that could be a deal breaker for many of the relationships these days,” Sara Nasserzadeh, PhD, a psychosexual therapist, told Healthline. Men are aware that in a sexual situation, there is a certain expectation, which can lead to things such as embarrassment and anxiety when those expectations aren’t met. The problem, explains Nasserzadeh, is that short-term erectile dysfunction can become more problematic if it stems from a psychological issue. That is, if every time a man has sex he gets nervous and worries he can’t perform and subsequently loses his erection, that process may become chronic. To take the blue pill or not?For a situation where a psychological barrier is having an effect on one’s physical ability, Nasserzadeh says that Viagra can actually be helpful.시알리스 구입 “If I’m convinced that he’s absolutely fine and it’s only the anxiety of not being able to maintain his erection with a partner, and if he reports that that was previously a source of embarrassment and distress from him in previous attempts, I would say go for it,” she said. However, while Viagra may have some legitimate use in younger men, it is also seen as problematic. “A lot of Americans want that instant gratification. I’m going to send a tweet immediately and I want a response in the next hour. I’m going to call you and expect you to pick up. I’m going to take a pill and it will work for me within twenty minutes,” Eric Garrison, a clinical sexologist at William and Mary College in Virginia, told Healthline. Yes, it will give you an erection, but the pill won’t necessarily take away all those feelings of anxiety and stress related to a sexual encounter. “That nervous piece, Viagra’s not going to get over that. They will still be nervous, but now they are just nervous with an erection,” Garrison said. Viagra is generally considered safe, but it can have health consequences and contraindications, particularly if taken as part of a night out. The drug lowers the user’s blood pressure, which is not an issue on its own, but if combined with other drugs with a similar effect, the results can be serious. Garrison notes the combination of Viagra and alkyl nitrites (commonly known as poppers), a common party drug, particularly among gay men, is especially dangerous. Whether or not drugs and alcohol are involved, Garrison explains that Viagra is a quick fix for dealing with issues of intimacy, and engaging in meaningful discussion with our partners about sex. https://viagra-onlineshop.com/ “In the United States, sex is always easier to do than to talk about,” he said. “It’s not about achievement or conquering or those other things. It’s all about pleasure and you can have sexual pleasure without an erection. You can have sexual pleasure without an orgasm, but we tend to think that you need that full Eiffel Tower in our pants.” 출처 : https://www.healthline.com/health-news/viagra-at-20-no-longer-an-older-mans-drug#1
The patient developed "persistent retinal toxicity" after taking far more than the recommended dose, Richard Rosen, MD, of New York Eye and Ear Infirmary of Mount Sinai in New York City, and colleagues wrote in Retinal Cases & Brief Reports.비아그라 구입 The patient in question presented at an urgent care clinic complaining of red-tinted vision in both eyes. He had begun experiencing the symptoms 2 days earlier after ingesting liquid sildenafil citrate he had purchased over the internet from a non-pharmacy source. The patient further reported that he drank the sildenafil directly from the bottle and didn't know the exact dosage he ingested, but that it was much more than the recommended 50 mg dose. Visual disturbances are known to be potential side effects of sildenafil citrate. For example, one study found that a single oral dose of 100-mg sildenafil citrate given to healthy young men "led to small but statistically significant transient changes of outer and inner retinal function" that resolved in 24 hours.시알리스 구입 Here, the patient's symptoms failed to improve in the year after initial diagnosis, despite a wide variety of treatments, which included -- upon presentation -- topical prednisolone acetate four times a day in both eyes, brinzolamide 1% three times a day in both eyes, and brimonidine tartrate twice daily in both eyes. A trial of oral prednisone 60 mg once a day for 3 days also resulted in no improvement. Rosen's group, using imaging such as optimal coherence tomography and adaptive optics, were able to see microscopic injury to the cones of the retina, the photoreceptor cells that are responsible for color vision. "To actually see these types of structural changes was unexpected, but it explained the symptoms that the patient suffered from," Rosen said in a release. "While we know colored vision disturbance is a well-described side effect of this medication, we have never been able to visualize the structural effect of the drug on the retina until now." The authors, noting that another single case study had shown that an excessive dose of sildenafil had resulted in retinal toxicity, suggested that "higher doses of sildenafil can lead to persistent retinal damage." But they also acknowledged that the fact the patient bought the sildenafil over the internet from a non-pharmacy source leads to concerns about the purity of the drug and the accuracy of its concentration -- "factors that might have contributed to the increased risk of toxicity." "Vision changes as a result of Viagra (sildenafil) administration have been a well-known side effect for many years, discovered during Viagra's preclinical trials before the drug's initial release," Nick Tadros, MD, director of Men's Health and Male Infertility at Southern Illinois University in Carbondale, told MedPage Today. Tadros, who was not involved in the current study, said it highlights an important potential side effect of unmonitored high-dose sildenafil use: "As the authors point out, it is important to realize that this man procured sildenafil of questionable quality from the internet without a physician's prescription and took several times more than the prescribed amount." He noted that there are no reported cases of permanent vision damage in patients taking sildenafil at the correct dosage.https://viagra-onlineshop.com/ "In my practice," Tadros continued, "I counsel patients about this potential risk and instruct them to discontinue the drug and report any vision changes. However, as long as patients are consuming the sildenafil from a provider and taking it as instructed, the chance of serious damage to their vision is exceedingly low." Rosen and colleagues reported relationships with Optovue, Optos, Heidelberg Engineering, Genentech, Spark Therapeutics, NanoRetina, Regeneron, Ocata Therapeutics, Guardion Health, Glauco-Health, Allergan, Boehringer-Ingelheim, CellView, and others 출처 : https://www.medpagetoday.com/urology/erectiledysfunction/75556 |
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